nDefense

nProbiotic Skin is a bio-optimized, encapsulated probiotic lysate that strengthens the skin’s microbiome and barrier, reduces inflammation, and enhances hydration. Ideal for sensitive or post-treated skin, it supports a balanced, resilient, and smoother complexion while promoting long-term skin health.

Clear Salicylic is an active ingredient developed with nanoencapsulated salicylic acid through the innovative nTechnology®. This system allows for aqueous-based cosmetic formulations with a translucent appearance, free of preservatives, ensuring greater stability and efficacy of salicylic acid. Salicylic acid has keratolytic, anti-inflammatory, comedolytic, and antimicrobial properties, making it effective in the treatment of acne, psoriasis, oil control, and combating photoaging. The nanotechnology applied to Clear Salicylic solves the challenges related to low water solubility and the instability of salicylic acid at neutral pH, increasing its stability and promoting deeper penetration into the skin.

Nanoencapsulated peppermint essential oil, neem oil, allantoin, soy isoflavones, and turmeric extract.
Recommended for products aimed at promoting skin refreshment and relaxation, reducing sensitivity, and treating acne and skin conditions.

nCurcumin Nutrition has curcumin encapsulated in a self- nanoemulsifiable system, capable of stabilizing and protecting this molecule from degradation and easily solubilizing it when in contact with the aqueous environment or directly in the fluids of the gastrointestinal tract, facilitating its absorption and increasing the oral bioavailability of the curcumin.

Vitamin K2 (menaquinone-7 or MK-7) is synthesized by intestinal bacteria and found in foods of animal origin and fermented foods. Essential for calcium metabolism, vitamin K2 plays a crucial role in bone and cardiovascular health. However, its low water solubility limits absorption in the gastrointestinal tract, especially in low-fat diets, with only about 10 to 15% of the oral dose being absorbed. nVitamin K2 Nutrition uses a 100% soluble nanoparticle system, which improves the stability of MK-7, allowing a controlled and gradual release, increasing its absorption, bioavailability and benefits for bone and cardiovascular health in a more effective and prolonged way.

Vitamin D3 (cholecalciferol) is a steroid hormone derived from cholesterol, crucial for bone metabolism, muscle function, gene expression, and the immune system. Sun exposure is the main source of vitamin D3, supplemented by some foods of animal origin. Due to the difficulty of obtaining adequate amounts through diet and sunlight alone, supplementation is recommended to ensure optimal levels in the body. nVitamin D3 Nutrition uses a nanoparticle system that increases the solubility of vitamin D in an aqueous medium by more than 300 times, facilitating its absorption in the GIT and resulting in greater bioavailability. Furthermore, it protects vitamin D against degradation by light, heat, and oxidation, increasing the stability and shelf life of the product. This technology allows the administration of D without oily vehicles, which is ideal for fat-restricted diets, ensuring efficient and convenient supplementation.

nVitamin B12 Nutrition is a dietary supplement that delivers vitamin B12 (methylcobalamin) using polymeric nanoparticles formulated with natural ingredients. Vitamin B12 plays a crucial role in the formation and maturation of red blood cells, helping to prevent anemia, and supports the nervous and cardiovascular systems. Since B12 is typically found in animal-based foods, supplementation is important for those with restricted diets or deficiencies. The use of polymeric nanostructures provides a stable matrix that protects the vitamin from light, heat, and extreme pH, enhancing product stability and shelf life. This delivery system also enables a controlled and sustained release, allowing the active ingredient to be gradually absorbed at the target location for improved effectiveness.

nAstaxanthin Nutrition enhances the action of astaxanthin, a powerful antioxidant encapsulated in lipid nanoparticles. Astaxanthin is extracted from microalgae, such as Haematococcus pluvialis, and is a xanthophyll known for its benefits, including photoprotection (protecting the skin from UV damage) and anti-inflammatory effects.By using lipid nanoparticle encapsulation, nAstaxanthin Nutrition increases the solubility of astaxanthin by 120,000 times, greatly improving its bioavailability and efficacy when taken orally. This technology enhances the absorption and effectiveness of the compound in the body, making it more impactful for health benefits.

Melatonin Nutrition is 4 times more soluble than conventional melatonin, significantly improving its absorption and effectiveness. Encapsulation brings about a prolonged effect to the active ingredient, slowly releasing it throughout the sleep, which, combined with its increased solubility and reduced size, contributes to better sleep duration and quality.

nCoQ10 Nutrition is a dietary supplement that enhances the benefits of Coenzyme Q10 (CoQ10), a powerful antioxidant crucial for mitochondrial bioenergetics, including electron transport, ATP synthesis, and cellular respiration. CoQ10’s physiological effects contribute to increased sports performance, cognitive enhancement, cardiovascular health, and reduced inflammation in chronic diseases. However, CoQ10 is notoriously poorly absorbed in the gastrointestinal tract, with only 1-3% of the ingested dose being absorbed. To overcome this challenge, nCoQ10 Nutrition delivers CoQ10 enriched with vitamin E in the form of a nanoemulsion. The use of natural, biocompatible ingredients and a 100% water-soluble formulation significantly improves the absorption and bioavailability of CoQ10, leading to more efficient use in the body.

Retinol palmitate is one of the most common forms of vitamin A found in tissues. While vitamin A is naturally obtained from food, a deficiency can impair tissue function, leading to issues such as vision loss, anemia, and a weakened immune response, particularly during critical stages of development like infancy, childhood, pregnancy, and lactation. As a result, vitamin A supplementation is recommended for both children and adults. nVitamin A is a retinyl palmitate nanoemulsion with an encapsulation efficiency of over 99%. This formulation enhances the solubility of retinyl palmitate by more than a million times, significantly improving its bioavailability and potential efficacy when taken orally. This advancement in solubility marks a major step forward in enhancing the absorption and effectiveness of vitamin A.

Composed of natural ingredients with insect and ectoparasite repellent properties, nCitronela Plus contains citronella essential oil, one of the most widely used natural repellents. The nanoencapsulation of essential oils in this formulation improves the stability of the active compounds by reducing their volatility and protecting them from oxidation, enhancing both their effectiveness and longevity.

nVitamin E contains tocopheryl acetate (vitamin E) encapsulated in lipid nanoparticles. Vitamin E is naturally found in the skin, but exposure to external oxidizing agents (e.g., ultraviolet radiation) significantly reduces the levels of vitamin E in the skin. Therefore, the topical application of this vitamin has been shown to be extremely beneficial for protecting the skin against oxidative damage caused by everyday external agents. Vitamin E acts by protecting the skin against effects induced by solar radiation, reducing the occurrence of erythema, edema, burns, lipid peroxidation, gene mutation, collagen damage, immunosuppression, and even skin cancers. Reduced skin sensitivity is also achieved with the use of vitamin E after sun exposure. Therefore, the combination of vitamin E with sunscreens and post-sun formulations enhances product effectiveness.

Palmitate retinol is the primary form of vitamin A found in the skin. However, factors such as sun exposure can lead to epidermal vitamin A deficiency, highlighting the importance of its topical application. One of the main benefits of topical vitamin A is its ability to normalize keratinization and regulate the growth and differentiation of epithelial cells. Vitamin A stimulates the production of collagen and hyaluronic acid, assists in the renewal of epidermal cells, controls cutaneous bacterial flora, and absorbs ultraviolet radiation, protecting cellular targets and preventing damage and oxidative stress.

nOmegas contains a blend of active ingredients rich in essential fatty acids (EFAs), such as alpha-linolenic acid (omega-3), linoleic acid (omega-6), and arachidonic acid, encapsulated in lipid nanoparticles. It includes vegetable oils, such as flaxseed oil (Linum usitatissimum) and sunflower oil (Helianthus annuus), combined with purified essential fatty acids. The topical application of EFAs has been recommended to promote skin hydration, restoring physiological balance and the barrier function of the stratum corneum, favoring the maintenance of skin integrity. In veterinary medicine, EFAs-rich ingredients are widely used as adjuvants in the treatment of atopic dermatitis.

nOjon contains ojon oil encapsulated in lipid nanoparticles with an average size of 200 nm. The cosmetic application of ojon oil is attributed to its excellent emollient property. Due to its composition similar to lipids found in hair fibers, ojon oil assists in complete hair reconstruction. Additionally, it has beneficial effects on skin hydration and prevention of transepidermal water loss, restoring its softness, smoothness, and elasticity. Thanks to its nanometric size, nOJON penetrates deeply into the animal’s skin and fur, improving the effectiveness of the active ingredient. It also provides a gradual release of the active ingredient when applied to the animal, resulting in a longer-lasting effect.

nNeem contains nanoencapsulated neem oil recommended for insect and ectoparasite repellency. Neem oil is obtained from the seeds of the Azadirachta indica tree and is predominantly composed of fatty acids (oleic, palmitic, and stearic acids). Used for years as a medicinal plant, neem oil contains over 100 biologically active compounds. It is recognized for the presence of triterpenoids, compounds with insecticidal properties effective in reducing the population of various pests. In veterinary medicine, neem oil has been widely used for repelling fleas, mites, and ticks.

Nanoencapsulated tea tree essential oil.
Recommended for products with antimicrobial and oiliness reduction purposes.

Blend of nanoencapsulated coconut oil, argan oil, and avocado oil.
Recommended for products aimed at deep hydration of fur and skin, especially for dogs with sensitive or atopic skin.

nPhytosphingosine contains phytosphingosine encapsulated in lipid nanoparticles with an average size of 200 nm. This nanometric size enhances the penetration of the active ingredient into the animal’s skin and fur, while also allowing for gradual release. Upon application, the lipid nanoparticles form an occlusive layer on the skin that helps prevent water loss and supports skin hydration. Phytosphingosine is a naturally occurring sphingoid base found in the stratum corneum, playing a key role in maintaining healthy skin. Its topical application increases ceramide levels and strengthens the skin’s barrier function, which is especially important for managing conditions like dry skin and atopic dermatitis in animals. Due to these properties, phytosphingosine is commonly used in veterinary dermatological products for sensitive or atopic skin, including shampoos, conditioners, lotions, and sprays.

nCoating is composed of a blend of 100% natural origin actives encapsulated in polymeric nanoparticles, recommended for maintaining the cleanliness and hydration of the skin and fur. It forms a protective barrier against the deposition of particles and dirt, keeping the animal’s fur clean for a longer time. It has cleaning and disinfecting action while moisturizing and protecting the applied area. Its composition includes highly moisturizing actives, such as coconut oil and almond oil, as well as a combination of 100% plant-based ingredients that provide emollience and form a long-lasting protective film. nCoating also contains melaleuca essential oil with potent antimicrobial action.

nChlorhexidine has chlorhexidine encapsulated in moisturizing nanoparticles for incorporation into topical veterinary products. Scientific studies prove that chlorhexidine nanoencapsulation increases the absorption of the drug in the stratum corneum, in addition to allowing a sustained release resulting in a longer lasting action when compared to free chlorhexidine. The superior action of nanoencapsulated chlorhexidine is related to the increased delivery of the drug due to the prolonged contact of the nanocarrier system with the bacteria of the skin and follicles. Chlorhexidine is widely used in topical veterinary products with antimicrobial action, and is indicated in the treatment of skin conditions caused by fungi and bacteria. Applications: shampoos, lotions, sprays and ear solutions.

Chamomile oil encapsulated in lipid nanoparticles.
Recommended for use in hygiene products for animals with light-colored fur, as well as in cleaning solutions for the periocular and muzzle areas.

The product nCalendula contains calendula oil and shea butter combined in lipid nanoparticles with an average size of 200 nm. Calendula oil is obtained from the flowers of the Calendula officinalis L. plant and exhibits anti-inflammatory, antioxidant, antiseptic, and emollient properties. It also has a healing effect in the treatment of wounds, burns, and skin cracks. Shea butter is an excellent emollient with anti-irritant, anti-inflammatory, and antioxidant properties. The nanometric size allows for better penetration of the actives into the skin and animal fur, increasing their effectiveness and forming a protective and moisturizing layer at the application site.

A blend of natural antioxidants, rich in polyphenols derived from grapes. It has high antioxidant potential and tyrosinase inhibition, protecting the skin from free radicals and UV radiation, providing an anti-aging and skin-lightening effect. The nanoencapsulation of resveratrol protects the encapsulated active against degradation and releases it in a controlled manner, increasing its action time on the skin.

With an exclusive blend of vitamin C and red fruits, nVitamin C combines ascorbyl palmitate with acai and raspberry oils, rich in vitamin C and other natural antioxidant compounds, encapsulated in lipid nanoparticles. Ascorbyl palmitate is the fat-soluble form of vitamin C, topically used for smoothing out fine lines and rejuvenating the skin, as it protects the skin against free radicals and external aggressions. Another benefit of topical vitamin C application is cellular regeneration by stimulating collagen synthesis, improving skin texture and firmness. The nanoencapsulation process of G-Vitamin C is one of the most promising technologies for protecting the active ingredients from degradation, increasing the stability of the encapsulated active in the final product and during storage.

Tranexamic acid has functional skin lightening activity in the treatment of melasma, as it can inhibit melanin synthesis by blocking the plasminogen/plasmin pathway, thereby preventing the interaction between melanocytes and keratinocytes. Additionally, it can promote skin exfoliation, leading to the regeneration of epidermal and dermal tissues and the reduction of pigmentary discolorations. Tranexamic has an average size of 200 nm, allowing for a more gradual and prolonged release of the encapsulated active ingredient, reducing skin irritability.

Topical application of vitamin E is extremely beneficial for protecting the skin against oxidative damage caused by free radicals and everyday external agents. Due to its ability to neutralize free radicals, it acts to protect the skin against various harmful effects induced by solar radiation. Topical application of vitamin E increases the concentration of free tocopherol in the skin, providing protection against sunburn. Nanoencapsulation allows for the easy dispersion of lipophilic actives like tocopheryl acetate (oily vitamin E) in aqueous media, enabling the development of formulas with a pleasant and non-greasy sensory experience. Additionally, lipid nanoparticles form an occlusive layer on the skin, preventing transepidermal water loss and assisting in maintaining skin hydration.

Thioglycolic acid encapsulated in lipid nanoparticles, with the market’s lowest odor!
Recommended for products aimed at treating skin hyperpigmentations, especially dark circles.

Topical vitamin A in the form of retinol plays a crucial role in the cellular restoration and regeneration process, necessary for growth, differentiation, and keratinization. By stimulating cell proliferation, it thickens the skin, improving roughness and fine wrinkles. Retinol can also be used in treatments for acne, oily skin, and rosacea. Additionally, it has the ability to alter the functioning of aged cells so that they behave like younger cells. However, retinol is poorly soluble in water (lipophilic), unstable in the presence of light or heat, and thus needs to be stabilized in nanostructured formulations to protect it during handling and storage. Moreover, nanoencapsulation enhances its effectiveness and reduces skin irritations, such as excessive redness, photosensitivity, and irritation.

Exclusive blend of lavender essential oil, geranium essential oil, and aloe vera extract in lipid nanoparticles that promote hydration, relaxation, and cellular balance.
Recommended for massage, aromatherapy, wellness, and relaxation products.

Phytosphingosine and avocado oil encapsulated in lipid nanoparticles.
Recommended for products with antimicrobial, anti-inflammatory, and restoration of skin barrier integrity purposes.

Nanoencapsulated Niacinamide (active vitamin B3) for topical use.
Recommended for products aimed at blue light protection, acne treatment, skin barrier regeneration, anti-inflammatory and antioxidant action, hydration, and skin tone uniformity.

Blend of tea tree essential oil, clove essential oil, sunflower oil, d-panthenol, and nanoencapsulated white tea extract.
Recommended for products aimed at cuticle hydration and revitalizing and antimicrobial action on nails.

Kojic acid encapsulated in lipid nanoparticles.
Recommended for products with a depigmenting and skin spot-lightening purpose.

Coconut, almond, and ginger oils, soy glycerides, and shea unsaponifiables encapsulated in lipid nanoparticles.
Recommended for products aimed at promoting shine, softness, and long-lasting protection to hair strands.

Argan oil encapsulated in lipid nanoparticles.
Recommended for products with moisturizing and emollient purposes for hair and skin.

Coenzyme Q10 encapsulated in lipid nanoparticles.
Recommended for products with anti-wrinkle and skin-firming purposes.

Blend of alpha-bisabolol and chamomile oil encapsulated in lipid nanoparticles.
Recommended for products aimed at relieving symptoms of topical inflammation, such as post-sun, post-depilatory, or shaving procedures, or allergic skin reactions.

Caffeine, Green Coffee Oil, Arnica montana Oil, and Centella asiatica Extract nanoencapsulated.
Recommended for products with anti-cellulite and circulation-stimulating purposes for the periocular area and scalp.

Avocado oil encapsulated in lipid nanoparticles.
Recommended for products with moisturizing, emollient, soothing, and softening purposes.

Andiroba, babassu, and copaiba oils encapsulated in lipid nanoparticles, 100% natural and organic.
Recommended for products aimed at controlling scalp oiliness and flakiness and hair repair.

Brazil nut oil, pracaxi oil, tucuma butter, and ucuuba butter encapsulated in lipid nanoparticles, 100% natural and organic.
Recommended for products aimed at intense and deep skin hydration.

Blend of alpha-hydroxy acids (glycolic, malic, citric, and lactic acids) encapsulated in lipid nanoparticles.
Recommended for products aimed at maintaining skin health, improving skin firmness and elasticity, as well as providing moisturizing, stimulating corneal layer renewal and collagen synthesis, brightening, and antioxidative activity.

Polymeric melatonin micelles.
Recommended for products with antioxidant purposes, preventing skin aging, and acting as an adjuvant in photoprotection.

DMAE (Dimethylaminoethanol) is known for its anti-wrinkle and skin-firming effects, delivering visible lifting, brightness, and reduction in fine lines and dark circles. Encapsulated in 10–50 nm micelles, it ensures deep skin penetration, gradual release for prolonged efficacy, odor reduction, and enhanced stability for an improved sensory experience.

Polymeric micelles of hyaluronic acid with high permeation capacity.
Recommended for products aimed at skin tightening, anti-wrinkle effects, and aging prevention.

Combination of ferulic acid, vitamin C (2-glycosyl ascorbic acid), and vitamin E (tocopherol acetate) nanoencapsulated in polymeric micelles.
Recommended for products with antioxidant, toning, brightening, and skin-evening purposes.

Polymeric micelles of cysteamine.
Recommended for products with the purpose of skin hyperpigmentation lightening.