CONNAPIC

A patented active derived from Connarus semidecandrus, a medicinal plant traditionally used across Southeast Asia. It offers strong anti-inflammatory, anti-allergy, and anti-atopic properties. Proven in vitro to reduce β-hexosaminidase (allergy), nitric oxide (inflammation), and TARC expression (itching), while increasing filaggrin for barrier support. An ideal natural active for sensitive, itchy, inflamed, or atopic skin.

INCI Name

Water, Butylene Glycol, Connarus Semidecandrus Leaf Extract
ConnAPIC functional skincare active with anti-inflammatory and postbiotic properties

Benefits & Applications

  • Liquid
  • Patented Plant Extract
  • Anti-Inflammatory
  • Anti-Allergy / Anti-Atopy
  • Sensitive Skin Actives
  • Barrier-Repair
  • Inhibits β-hexosaminidase release
  • Reduces NO production in macrophages
  • Lowers TARC gene expression (
  • Increases filaggrin gene expression
  • Alleviates redness, itching, and dryness associated with atopic skin
  • Suitable for scalp, face, and body use in sensitive skin care

  • Atopic or eczema-prone skin creams
  • Anti-inflammatory repair serums
  • Scalp soothing lotions or treatments
  • Barrier-restoring moisturizers
  • Anti-itch body or facial formulations
  • Asia Pacific
  • Europe
  • Latin America
  • North America
  • Calmer, less irritated skin with reduced itch and redness
  • Stronger moisture barrier, especially in atopic skin
  • Soothing daily care for reactive or allergy-prone skin
  • Relief from chronic dryness and sensitivity
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