CONNAPIC

A patented active derived from Connarus semidecandrus, a medicinal plant traditionally used across Southeast Asia. It offers strong anti-inflammatory, anti-allergy, and anti-atopic properties. Proven in vitro to reduce β-hexosaminidase (allergy), nitric oxide (inflammation), and TARC expression (itching), while increasing filaggrin for barrier support. An ideal natural active for sensitive, itchy, inflamed, or atopic skin.

INCI name

Water, Butylene Glycol, Connarus Semidecandrus Leaf Extract
ConnAPIC functional skincare active with anti-inflammatory and postbiotic properties

Benefits & Applications

Physical form at 25°C

  • Liquid

Functions

  • Patented Plant Extract
  • Anti-Inflammatory
  • Anti-Allergy / Anti-Atopy
  • Sensitive Skin Actives
  • Barrier-Repair

Category

  • Inhibits β-hexosaminidase release
  • Reduces NO production in macrophages
  • Lowers TARC gene expression (
  • Increases filaggrin gene expression
  • Alleviates redness, itching, and dryness associated with atopic skin
  • Suitable for scalp, face, and body use in sensitive skin care

Applications

  • Atopic or eczema-prone skin creams
  • Anti-inflammatory repair serums
  • Scalp soothing lotions or treatments
  • Barrier-restoring moisturizers
  • Anti-itch body or facial formulations

Regional availability

  • Asia
  • Europe
  • Latin America
  • N America

Consumer benefit

  • Calmer, less irritated skin with reduced itch and redness
  • Stronger moisture barrier, especially in atopic skin
  • Soothing daily care for reactive or allergy-prone skin
  • Relief from chronic dryness and sensitivity

Related Products

VegSYRUP-2 plant-based syrup moisturizing and barrier support active

VegSYRUP-2

Researchers tested the barrier effect by measuring caffeine permeation in a three-dimensional reconstructed human epidermis model. The polysaccharide blend showed a strong protective action. Compared to the control, it reduced

learn more
Mediterranean Whitening Brightening Natural Whitening Active

Mediterranean Whitening

Mediterranean Whitening works by targeting the key enzyme involved in melanin production—tyrosinase. During melanogenesis, melanocytes naturally generate hydrogen peroxide, which can trigger oxidative stress and lead to the formation of

learn more
SCH Actives B-TOX peptide lifting skincare ingredient

SCH Actives™ B-TOX

Actives™ B-TOX blends advanced peptides to reduce wrinkles and restore firmness. Acetyl hexapeptide-8 relaxes facial muscles, while Palmitoyl pentapeptide-4 stimulates collagen production. Together, they smooth expression lines and improve skin

learn more