Skinactive B5

Skinactive B5 (also known as D-Panthenol / pro-vitamin B5) is a water-soluble vitamin that is naturally found in the skin. It is a precursor to pantothenic acid, which is a B vitamin that is essential for many bodily functions, including skin health.

It’s low molecular weight can help penetrate deep into the skin, improving skin texture and providing strong moisturizing benefits. It also promotes epithelial cell growth, which can help to accelerate wound healing and repair sunburn, eczema, and baby diaper eczema.

Skinactive B5 is made by chemically modifying the amino acid alanine. The reaction is catalyzed by an enzyme called panthenol dehydrogenase. The resulting product is a white to off-white powder that is soluble in water and alcohol.

INCI name: D-Panthenol

Other name: Dexpanthenol;Provitamin B5
CAS: 81-13-0
Appearance: colorless to light yellow liquid

Anthenol is easily absorbed into the skin and quickly converted into Pantothenic acid through oxidation. Pantothenic acid is then distributed into the cells where it is converted to Acetyl Coenzyme-A (Acetyl CoA) in the cells of the epidermis. Vitamin B5 is essential for the synthesis of Acetyl CoA, which plays a crucial role in many biochemical reactions necessary for life, such as the maintenance and repair of all cells. Acetyl CoA also helps break down fats, carbohydrates, and proteins to produce carbon dioxide, water, and energy. Additionally, it is involved in the synthesis of fatty acids and sphingolipids, which are important for maintaining the lipid layers of the stratum corneum and the integrity and fluidity of cell membranes.

Product Features

  • Maintains a healthy skin: right balance between the stem cell renewal and the cell differentiation (p63 upregulated)
  • Increases stratum corneum hydration by inducing long-lasting skin moisturization
  • Reinforces the skin barrier by reducing transepidermal water loss (TEWL)
  • Panthenol is produced with the highest standards in Dalry,
  • Panthenol forms show very good compatibility with all groups of cosmetics ingredients

Benefits

  • Regenerates healthy skin maintaining cell stemness
  • Improvement symptoms of sensitive skin:
    dryness, roughness, redness, pruritus
  • Accelerates wound-healing
  • Moisturizes hair, strengthens damaged hair and reduces split ends
  • Reinforces the nails
  • Improves hydration and maintain skin softness and elasticity

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