INCI name: Polyquaternium-51

Polyquaternium-51 is a synthetic, polymeric quaternary ammonium compound. This means it is a large molecule with unique amphiphilic (water- and oil-loving) properties and has a charge that gives it conditioning and film-forming properties for skin and hair. Its humectant properties stem from its structural similarity to lipids found in the surface cells of human skin, known as corneocytes. As a result, it works to preserve the skin's barrier and helps prevent water loss. In skincare products, the typical usage levels of polyquaternium-51 range from 0.5% to 5%, with concentrations of 2% to 5% most often used in rinse-out hair care products like conditioners. Smaller amounts, such as 0.021% to 0.05%, may be used in products like eye makeup or 0.02% in moisturizers. While a formal safety assessment hasn't been published, a draft report exists which does not indicate that polyquaternium-51 poses a risk to the skin in the amounts currently used.

INCI name: Acetyl Glucosamine

Skinactive Glucosamine, Acetyl glucosamine (also known as N-acetyl glucosamine or NAG), is a naturally occurring amino sugar that is found in the body. It is a precursor to hyaluronic acid, which is a substance that helps to keep the skin hydrated and plump. Acetyl glucosamine is also known to have anti-inflammatory and antioxidant properties.

INCI name: Carboxymethyl Chitosan

Skinactive CMC, also known as carboxymethyl chitosan (CMC), is a water-soluble derivative of chitosan, a natural polysaccharide derived from chitin. CMC is created by reacting chitosan with carboxymethyl groups, a process catalyzed by an acid, such as hydrochloric acid. The resulting product is a white to off-white powder that can dissolve in water and alcohol. Carboxymethyl chitosan is a derivative of chitosan that has been extensively researched due to its water solubility in a wider pH range compared to the original compound. This extended solubility has increased its potential for various applications. In this review, the different preparation conditions resulting in N- and O-carboxylated chitosan, diverse degrees of substitution, and water solubility are summarized. Five important features of carboxymethyl chitosan from recent studies, including moisture absorption-retention, antimicrobial properties, antioxidant capacities, delivery system, and emulsion stabilization, are highlighted for potential cosmetic use. Additionally, comprehensive information on its cytotoxicity has been included to ensure its safety in application.

INCI name: D-Panthenol

Panthenol, a vitamin ingredient, is highly valued in skin and hair care applications due to its moisturizing properties. It has anti-inflammatory effects and can soothe irritated and sensitive skin. In hair care, it is known for its humectant properties and its ability to improve the hair's resistance to mechanical stress.

INCI name: Saccharide Isomerate

Skinactive SA is a new moisturizing component that is different from any previous moisturizer. It is similar to hyaluronic acid in its action mechanism, but it has some unique properties that make it even more effective.

INCI Line: Sodium Polyglutamate (700kDa)

Grand polyglutamate (700 kDa) is a viscous polymer of amino acids, commonly found in the form of sodium salts. Its structure comprises amino acid units linked by peptide bonds formed through α-amino and γ-carboxyl groups. This unique composition includes a significant number of side chain carboxyl acids that can establish hydrogen bonds within or between molecules.

INCI Line: Sodium Polyglutamate (10kDa)

Grand Polyglutamate (10kDa) is a variant of the viscous polymer of amino acids, typically in the form of sodium salts. Building upon the benefits of the larger molecular weight version, Grand Polyglutamate (10kDa) offers additional advantages for the skin.

INCI Name : Ceramide NP

SkinCera NP, also known as Ceramide NP, is a naturally occurring lipid molecule that belongs to the ceramide family. It is an essential component of the skin’s barrier function and plays a crucial role in maintaining skin health and integrity. Ceramide NP is commonly used in skincare formulations for its various benefits.