Grand Azelaic

Grand Azelaic acid is a naturally occurring dicarboxylic acid that is found in wheat, barley, and rye. It is also available as a synthetic ingredient in skincare products. Azelaic acid is a white to off-white powder that is soluble in water and alcohol.

INCI name: Azeleic Acid

CAS: 123-99-9
Appearance: White crystal powder

Azelaic acid’s mechanism of action is to involve the inhibition of hyperactive protease activity. It is employed to treat mild to moderate acne, both comedonal and inflammatory, by eliminating acne-causing bacteria in skin pores and reducing keratin production, a substance that facilitates bacterial growth.
Additionally, azelaic acid is used as a topical gel for rosacea due to its anti-inflammatory properties, which help clear bumps and swelling associated with the condition.
In pharmaceutical and scientific applications, azelaic acid is typically used in concentrations of 15% to 20%, where it is considered as effective as benzoyl peroxide 5%, tretinoin 0.05%, erythromycin 2%, and oral
tetracycline at 500 mg – 1000 mg.
Comparative studies have shown that azelaic acid has more high-quality evidence of effectiveness than salicylic acid, nicotinamide, sulfur, zinc, and alpha-hydroxy acids. It is also used to treat skin pigmentation issues such as melasma and post-inflammatory hyperpigmentation, especially in darker skin types, and is recommended as an alternative to hydroquinone. As a tyrosinase inhibitor, azelaic acid reduces melanin synthesis.

Grand Azelaic acid has a number of benefits in skincare. It can help to:

Treat acne:Grand Azelaic acid is an effective treatment for acne. It works by killing the bacteria that cause acne, as well as reducing inflammation.

Reduce hyperpigmentation:Grand Azelaic acid can help to reduce hyperpigmentation, which is the darkening of the skin that can be caused by acne, melasma, or sun damage.

Improve skin texture:Grand Azelaic acid can help to improve skin texture by exfoliating the skin and removing dead skin cells.

Reduce rosacea: Grand Azelaic acid can help to reduce the redness and inflammation associated with rosacea.

Moisturize the skin: Grand Azelaic acid can help to moisturize the skin by increasing the production of natural moisturizing factors.

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