CONNAPIC

A patented active derived from Connarus semidecandrus, a medicinal plant traditionally used across Southeast Asia. It offers strong anti-inflammatory, anti-allergy, and anti-atopic properties. Proven in vitro to reduce β-hexosaminidase (allergy), nitric oxide (inflammation), and TARC expression (itching), while increasing filaggrin for barrier support. An ideal natural active for sensitive, itchy, inflamed, or atopic skin.

INCI name

Water, Butylene Glycol, Connarus Semidecandrus Leaf Extract
REQUEST A SAMPLE
Material Safety Data Sheets
ConnAPIC functional skincare active with anti-inflammatory and postbiotic properties

Benefits & Applications

Physical form at 25°C

  • Liquid

Functions

  • Patented Plant Extract
  • Anti-Inflammatory
  • Anti-Allergy / Anti-Atopy
  • Sensitive Skin Actives
  • Barrier-Repair

Category

  • Inhibits β-hexosaminidase release
  • Reduces NO production in macrophages
  • Lowers TARC gene expression (
  • Increases filaggrin gene expression
  • Alleviates redness, itching, and dryness associated with atopic skin
  • Suitable for scalp, face, and body use in sensitive skin care

Applications

  • Atopic or eczema-prone skin creams
  • Anti-inflammatory repair serums
  • Scalp soothing lotions or treatments
  • Barrier-restoring moisturizers
  • Anti-itch body or facial formulations

Regional availability

  • Asia
  • Europe
  • Latin America
  • N America

Consumer benefit

  • Calmer, less irritated skin with reduced itch and redness
  • Stronger moisture barrier, especially in atopic skin
  • Soothing daily care for reactive or allergy-prone skin
  • Relief from chronic dryness and sensitivity

Related Products

Antioxca Strong Antioxidant Anti Aging Active

AntioxCA

Antiox-CA is a natural antioxidant complex made with synergistic actives of plant origin. It targets excess free radicals, the main driver of premature aging, and protects skin cells from oxidative

learn more
Jorange C Brightening Stable Vitamin C Active

JOrange-C

Formulated with α-hydroxy acids and natural active ingredients, JOrange-C enhances elasticity, restores brightness, and delivers an immediate lifting effect to the facial skin.

learn more
Coffee Beads exfoliant natural scrub ingredient

Coffee Beads

Coffee Beads are natural exfoliating granules produced from calibrated grinding of Coffea arabica beans. They are fully biodegradable and serve as a sustainable alternative to synthetic microbeads. In addition to

learn more